Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLEKDIERILISQEEIQVRCKELGKELTEIYQNTN------PLV-VGVLKGAVPFMADIVRSIDTY---LELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDIIDSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDYAEAYRNLPYIGVLKPSVYQSN 5K51 Chain:C ((19-198)) --------VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVEFLR-------------------------GKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY---

General information: TITO was launched using: RESULT: Template: 5K51.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 692 -21763 -31.45 -150.09 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.78 3D Compatibility (PKB) : -31.45 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.470

(partial model without unconserved sides chains): PDB file : Tito_5K51.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5K51-query.scw PDB file : Tito_Scwrl_5K51.pdb: