Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQSGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSVQGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEVEEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVN-AREIEVGLLGNY--DVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFRAIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDLAKESFDKREAHLI 2ZDG Chain:C ((1-318)) --MRVLLIAGGVSPEHEVSLLSAEGVLRHIP-FPTDLAVIAQDGR--WLLGEKALTALEAKAAPEGEHPF---PP---PLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPP-------VVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYE--APFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLA-EGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELAL-----------

General information: TITO was launched using: RESULT: Template: 2ZDG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1822 -108790 -59.71 -345.36 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -59.71 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.503

(partial model without unconserved sides chains): PDB file : Tito_2ZDG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZDG-query.scw PDB file : Tito_Scwrl_2ZDG.pdb: