Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFHGKITREQAERLLYPPE-TGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFE 1FYR Chain:B ((13-64)) WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVL---------------

General information: TITO was launched using: RESULT: Template: 1FYR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 175 -12449 -71.14 -244.10 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -71.14 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.721

(partial model without unconserved sides chains): PDB file : Tito_1FYR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FYR-query.scw PDB file : Tito_Scwrl_1FYR.pdb: