Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAG------KNP-ILVGILKGSIPFMAELVK-----HIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDIIDTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDYKENYRNLPYIGVLKEEVYSN 5K51 Chain:C ((19-198)) --------VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVE--FLR-------------------------GKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY--

General information: TITO was launched using: RESULT: Template: 5K51.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 676 -27105 -40.10 -189.54 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain C : 0.77 3D Compatibility (PKB) : -40.10 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_5K51.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5K51-query.scw PDB file : Tito_Scwrl_5K51.pdb: