Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLVTAIVKPFKLDDVREALSDIGVQGITVTEVKGFGRQKGHTELYRGAEYVVDFLPKVKIEIAISDEMVDAVIESITRVASTGKIGDGKIFLTNLEQVIRIRTGETGPDAV 3TA1 Chain:A ((1-106)) MKMVVAVIRPEKLECVKKALEERGFVGMTVTEVKGRGEQKGIRLQFRG--VEVDLLQKTKVEVVVSDDAVDEVVEAIVSSARTGKFGDGRIFVIPVEKSVKIRTGD------

General information: TITO was launched using: RESULT: Template: 3TA1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 380 -52576 -138.36 -505.53 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -138.36 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.594

(partial model without unconserved sides chains): PDB file : Tito_3TA1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TA1-query.scw PDB file : Tito_Scwrl_3TA1.pdb: