Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENDMKKISLVIAASTMSLSVFAAAPITNKSPAKDQFSYSYGYLMGRNNTDALTDLNLDIFYQGLQEGAQNKTARLTDEEMAKAINDYKKTLEAKQLVEFQKQGQQNAQAGAAFLAENTKKSGVITTKSGLQYQVLKEGTGKT-PKATSRVKVNYEGRLLDGTVFDSSIARNHPVDFQLN--QVIAGWTKGLQTMKEGGKTRFFIPAKLAYGEVGAGDSIGPNSTLIFDIELLQVLPK 3UQI Chain:A ((2-107)) ---------------------------------------------------------------------------------------------------------------------------------GVQVVTLAAGDEATYPKAGQVAVVHYTGTLADGKVFDSSRTRGKPFRFTVGRGEVIRGWDEGVAQMSVGQRAKLVCSPDYAYGSRGHPGVIPPNATLTFDVELLRV---

General information: TITO was launched using: RESULT: Template: 3UQI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 500 9987 19.97 96.96 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 19.97 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.559

(partial model without unconserved sides chains): PDB file : Tito_3UQI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UQI-query.scw PDB file : Tito_Scwrl_3UQI.pdb: