Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAEEHALTSPEYIKHHLTNMTYGKMPDGTWKLAETAEEAHSMGFTAIHLDSMGWSIGLGVIFCLLFWIVARAANAGVPTKFQSAIEMIIEFVDSSVRDTFHGKSRLIAPLALTIFVWIFLMNLMDLIPVDWIPQVAAFVGA-NAFGMDPHHVYFKIVPSTDPNITLGMSLSVFVLILFYSIREKGVGGFVGELALNPFNPSNPVAKALLIPVNLILELVTFLARPISLALRLFGNMYAGELIFILI-----ALLPF-----WIQWALSVPWAIFHILVITLQAFIFMMLTIVYLSMASEKH 5FIL Chain:W ((78-222)) ------------------------------------------------------------------------------------------------------------------------------------------FIGSTNLLGLLPH----SFTPTTQLSMNLGMAIPLWAGAVITGFRNKTKASLAHFL---PQGTPTP-----LIPMLVIIETISLFIQPMALAVRLTANITAGHLLIHLIGGATLALMSISTTTALITFTILILLTILEFAVAMIQAYVFTLLVSLYL-------

General information: TITO was launched using: RESULT: Template: 5FIL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain W - contact count / total energy / energy per contact / energy per residue : 398 -71746 -180.27 -535.41 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain W : 0.61 3D Compatibility (PKB) : -180.27 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.308

(partial model without unconserved sides chains): PDB file : Tito_5FIL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5FIL-query.scw PDB file : Tito_Scwrl_5FIL.pdb: