Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGHRLSKIYTRTGDSGTTGLGDGSRVAKDDLRIAALGDVDELNAIIGVLRAQI-TDSQVANKADWDKSLSLIQHWLFDLGGEVCIP------NYNLLQPVCIEFLEKEIDCMNEDLPMLKEFILPSGSLSCSYAHQARAVCRRAERSLMSVQSCDQNIQATALQLLNRLSDWLFVASRALQRAEGGQEVLWQKNINEMI 3CI3 Chain:A ((7-187)) -----VKIYTKNGDKGQTRIIGKQILYKNDPRVAAYGEVDELNSWVGYTKSLINSHTQVLSN-----ELEEIQQLLFDCGHDLATPADDERHSFKFKQEQPTVWLEEKIDNYTQVVPAVKKFILPGGTQLASALHVARTITRRAERQIVQLMREEQ-INQDVLIFINRLSDYFFAAARYANYLEQQPDMLYR-------

General information: TITO was launched using: RESULT: Template: 3CI3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 724 -42269 -58.38 -242.92 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -58.38 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_3CI3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CI3-query.scw PDB file : Tito_Scwrl_3CI3.pdb: