Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIFSLIAFAVCLSLQGCMQHESIAHEHRPHDRGTLVSQTHNFYQISNDVFRSEQPDAAMIPELKHHQIGTIINLRAKASDDLVFKNENFNLIHIPI--NTWAIDRQDLLEVMQQIQLAKQNNQRVLLHCYHGSDRTGASVSMYRIIFENWVIDDAVKEMKQGGYGYHIIWKNIDRLFTPENVKWIQQQLSNPS 3CM3 Chain:A ((34-129)) --------------------------------------------RVTNNVYLGNYKNAMDAPS-SEVKFKYVLNL---TMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSKCDQRNEPVLVHSAAGVNRSGAMILAY--------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3CM3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 418 -42091 -100.70 -447.78 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -100.70 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_3CM3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CM3-query.scw PDB file : Tito_Scwrl_3CM3.pdb: