Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVTSVNPATNATNEYYLTRQSQMESNVRSYPRKLPLAIAKAQGCWVTDVEGTQYLDCLAGAGTLALGHNHPAVIQSIQDTLASGLPLHTLDLTTPLKDAFTEALLAYLPGGKEEYCLQFCGPSGADATEAAIKLAKTYTGRSSVISFSGGYHGMTHGSLAMTGNLSAKNAVNGLMPGVQFMPYPHEYRCPLGLGGEAGVDALTYYFENFIEDVESGVTKP-AAVILEAIQGEGGVVTAPVKWLQKIREVTEKHNIVLILDEVQAGFARSGKMFAFEHAGIEPDVVVMSKAVGGGLPLAVLGIKRKFDAWQP-AGHTGTFRGNQLAMGTGLVVLETIKEQNLAQNAQERGEFLQAELKKLATEFPCIGNVRGRGLMIGVEIVDERKPADRIGSHPADSQLAAAIQTACFNNKLLLEKGGRNGTVIRLLCPLIITQEECVEVIARFKKAVAEALVAVRGA 1VEF Chain:A ((29-395)) ------------------------------------LLIVRGQGARVWDAEGNEYIDCVGGYGVANLGHGNPEVVEAVKRQ-AETLMAMPQTLPTPMRGEFYRTLTAILP---PELNRVFPVNSGTEANEAALKFARAHTGRKKFVAAMRGFSGRTMGSLSVTWEPKYREPFLPLVEPVEFIPY------------------------NDVEALKRAVDEETAAVILEPVQGEGGVRPATPEFLRAAREITQEKGALLILDEIQTGMGRTGKRFAFEHFGIVPDILTLAKALGGGVPLGVAVMREEVARSMPKGGHGTTFGGNPLAMAAGVAAIRYLERTRLWERAAELGPWFMEKLRAIPS--PKIREVRGMGLMVGLELKEKAAP---------------YIARLEKEHRVLALQAG--PTVIRFLPPLVIEKEDLERVVEAVRAVLA---------

General information: TITO was launched using: RESULT: Template: 1VEF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2267 -84128 -37.11 -230.49 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -37.11 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.505

(partial model without unconserved sides chains): PDB file : Tito_1VEF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VEF-query.scw PDB file : Tito_Scwrl_1VEF.pdb: