Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNSLSEANTKFMFDLFQQFRKS-KENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 5CDZ Chain:A ((19-378)) -HKLAEANTDFAFSLYRELAKSSPDKNIFFSPVSISSALAMLSLGAKGDTHTQILEGLGFNS----------------EADIHQGFQHLLQTLNRPK-GLQLKTANGLFVDKSLKLLDSFLEDSKKLYQAEAFSVDFD--PEEAKKQINDWVEKQTNGKIKDLLKD--LDSDTVLVLVNAIYFKGKWKKPFDPENTKEEDFHVDEKTTVKVPMMSQKGKFYYYHDDELSCKVLELPYKG-NASMLIILPDE-GGLQHLEQSLTPETLSKW--LKSLTRRSVELYLPKFKIEGTYDLKEVLSNLGITDLFSPGADLSGIT-EEKLYVSKAVHKAVLEVNEEGTEAAAATGVEIVPRSPP----EFKADRPFLFLIRENKTGSILFMGKVVNP

General information: TITO was launched using: RESULT: Template: 5CDZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2099 47243 22.51 131.59 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : 22.51 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_5CDZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CDZ-query.scw PDB file : Tito_Scwrl_5CDZ.pdb: