Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIKQYLTA-TERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTGALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSFYAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESL-NFIGNVEARDLMNGVADVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLNYSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE 1VI1 Chain:B ((1-328)) -LRIAVDAMGGDHAPKAVIDGVIKGIEAFDDLHITLVGDKTTIESHLTTTSDRITVLHADEVIEPTDEPVRAVRRKKNSSMVLMAQEVAENRADACISAGNTGALMTAGLFIVGRIKGIDRPALAPTLPTVSGDGFLLLDVGANVDAKPEHLVQYAIMGSVYSQQVRGVTSPRVGLLNVGTEDKKGNELTKQTFQILKETA-NINFIGNVEARDLLDDVADVVVTDGFTGNVTLKTLEGSALSIFKMMRDVMTST-LTS--------PKLKEMKMKMEYSNYGGASLFGLKAPVIKAHGSSDSNAVFRAIRQAREMVSQNVAALIQEEVKE-

General information: TITO was launched using: RESULT: Template: 1VI1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1883 -21686 -11.52 -68.19 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain B : 0.87 3D Compatibility (PKB) : -11.52 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.526

(partial model without unconserved sides chains): PDB file : Tito_1VI1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VI1-query.scw PDB file : Tito_Scwrl_1VI1.pdb: