Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKTILVTGGTSYIGSHTVKALLNAGYQVHILDNLSTGNRAAVD-------SRASFKELDVYDASALKAYLEENQIDAVLHYTGEIVVSESIENPSKYFTANVAGMNQVLKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN-RYDWKYVIFRYFNVAGAEMDASNGLRVKN-PTHIIPNINKTALGQNDSLKIFGDDYDTRDGSCIRDYIYVLDLA 1XEL Chain:A ((3-240)) ----VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVNGTLRLISAMRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSKLMVEQILTDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIFGNDYPTEDGTGVRDYIHVMDLA

General information: TITO was launched using: RESULT: Template: 1XEL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1091 -24456 -22.42 -106.79 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -22.42 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.410

(partial model without unconserved sides chains): PDB file : Tito_1XEL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XEL-query.scw PDB file : Tito_Scwrl_1XEL.pdb: