Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPASMMMGMP--FLAFLSVVAVGFFASRVAAS-YTSRLRSDIFNRVLDYSQTEIKKFSIPSLLMRTTNDITQVQMLITMDLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTVLMTLAFPK--QSLIQGLTDKLNSITR---ESLTGIRVVRAYNAEDYQNEKFAAVNDELTR 3ZDQ Chain:A ((24-236)) ----AVGFLTMSSVISMSAPFFLGKIIDVIYTNPT-VDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMM-----FFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQ

General information: TITO was launched using: RESULT: Template: 3ZDQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 310 -37108 -119.70 -181.01 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -119.70 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.196

(partial model without unconserved sides chains): PDB file : Tito_3ZDQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ZDQ-query.scw PDB file : Tito_Scwrl_3ZDQ.pdb: