Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPK---TVVVGCDIRLSSEALKQAAIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPMDYNGMKLVRENARPISADTGLKE-IQALAETNNFEEVGQK-GTTQSYNILPEFVDHLLTYIEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNPILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQSGEKIVHDPRLVWNTFDIVDEYKGVTVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFRD--FAYCDSGMIPWLLTIVLLSETGQSLSTLVENMIAKFP---CSGEINFKVA-DTQTTIQKIFDFYADQNP-QIDRTDGVSLNFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQYYVDELTGLIQN 1PCM Chain:X ((12-445)) ----SIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIV------VAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAK--PMKVVVDCGNGVAGVIAPQLIEALGCSVIP-----LYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGF-DDGIYSAARLLEILSQDQRD----SEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIK------------

General information: TITO was launched using: RESULT: Template: 1PCM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 2695 15459 5.74 36.63 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain X : 0.76 3D Compatibility (PKB) : 5.74 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_1PCM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1PCM-query.scw PDB file : Tito_Scwrl_1PCM.pdb: