Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRLMINKSMKNIYIMGLLLACSGFAMAETVTQQPTGQPVRTASNPNAIRIVTRPEIMGLWGMEIPNNKKCVEYYNFRSSNDVVIKSGEEWSYGIYEYQPSDDPKEQLSALVMQIKFDNNKVDCSGQKQDQTGDISQYFVQWKNDHTINFCSTAKGEQCFATLRRMLP 1Y7X Chain:A ((1-113)) -----------------------------------GSHMQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFE-----------GPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTG---EEWLVTTVGAYL-----PAVFEEVLDLVDAVIL

General information: TITO was launched using: RESULT: Template: 1Y7X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 504 6523 12.94 57.73 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : 12.94 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.138

(partial model without unconserved sides chains): PDB file : Tito_1Y7X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y7X-query.scw PDB file : Tito_Scwrl_1Y7X.pdb: