Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKQIGVLQMRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQPNKEHMDMPSLHSLEHLTAELIRNHADY----IVDWSPMGCQTGFYLTVLNHESYEDILDVLEATMKDVL---EATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA 1J6W Chain:A ((4-149)) -------------LDSFKVDHTKMNAPAVRIAKTMLTPKGDNITVFDLRFCIPNKEILSPKGIHTLEHLFAGFMRDHLNGDSIEIIDISPMGCRTGFYMSLIGTPNEQKVSEAWLASMQDVLGVQDQASIPELNIYQCGSYTEHSLEDAHEIAKNVIAR---------

General information: TITO was launched using: RESULT: Template: 1J6W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 591 -19443 -32.90 -139.87 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -32.90 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_1J6W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1J6W-query.scw PDB file : Tito_Scwrl_1J6W.pdb: