Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEFTNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIA-MAEMGFQGIDINMGCPVPNVAERGKGSGLILRPEVAAQLIEA-AKAGGLPVSVKTRIGYTEMSEMEEWISHLLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGD----IPDRQTGEELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSITGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ 4XP7 Chain:A ((63-285)) -----------------------------------------NEVLSTVDFVAPDDRVVFRT----CEREQNRVVFQMGTS-DAERALAVARLVENDVAGIDVNMGCPKQ---------ALLSDPDKIEKILSTLVKGTRRPVTCKIRI-LPSLEDTLSLVKRIERTGIAAIAVHGRKREERPQHPVSCEVIK---AIADTLS--IPVIANGGSHDHIQQYSDIEDFRQATAASSVMVARAAMWNPSIFLKEGLRPLEEVMQKYIRYAVQYDNHYT----------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4XP7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 914 3324 3.64 15.98 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 3.64 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.339

(partial model without unconserved sides chains): PDB file : Tito_4XP7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XP7-query.scw PDB file : Tito_Scwrl_4XP7.pdb: