Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKG-----YNPINQI----VGYLL------SGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL 3SDV Chain:A ((306-384)) ----DNIVRLGIYRHFEKEIKEALDYVYRHWNERGIGWGRLNPIADLETTALGFRLLRLHRYNVSPAIFDNFKDA----------------------------

General information: TITO was launched using: RESULT: Template: 3SDV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 117 -9102 -77.79 -162.53 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -77.79 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.205

(partial model without unconserved sides chains): PDB file : Tito_3SDV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SDV-query.scw PDB file : Tito_Scwrl_3SDV.pdb: