Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLVVFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIAGAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIFSTIGY--GVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLWGLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVILGGILLGYMKTV 4QW2 Chain:A ((3-202)) EELVVEVR---------------GSN----------GAFYKAFVKDVHEDSITVAF--------ENNWQPDRQIPFHDVRF-------PPPVGYNKDINE-SDEVEVYSRANEKEPCCWWLAKVRMIKGE-----------------------------FYVIEYAACTYNEIVTIERLRSVNPNKPATKD--------TFHKIKLDVPEDLQQMCA---------KEAAHKDFKKAVG---AFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMR--

General information: TITO was launched using: RESULT: Template: 4QW2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 845 -71891 -85.08 -366.79 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -85.08 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.271

(partial model without unconserved sides chains): PDB file : Tito_4QW2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QW2-query.scw PDB file : Tito_Scwrl_4QW2.pdb: