Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMSLHRYKGKYMSNKRIAIIGAGPAGLMAAEVLSQYAYEIDVFEQKP--------SAARKFL----MAGKTGLNISHAEPLPQFIERY---DHTEWLKPWVEKWDAVWIQKWM-KSLGIES-----YVGTSGR------IFPVEMKAAPL---------------------------LRAWLKRLAEQQV---KFFYR-----HRCINLQGTTVTLENQNNQSTETFTQQYDAVILACGAVSWSQLGSDGAWQQWMDQSSIEPFQASNAGVLHTWSAFMESCFGEPLKRINAWVEPSQVTHGDIVITHYGLESGVIY---------------KLGRALREQQKQGKSLNLFLDL------------LPDVELTQLVKKLQASKKQSLTNIWRKAGLDTAKINLIREVVDKALWS-----------------QPETMAQKMKALQIKLDGFRPIEEAISCAG---GVKQDALTESLEL--KQTSGVFCCGE----MLDWDAPTGGYLLTACFATGRAAGEGVHSFLEK 4C3X Chain:A ((23-530)) ---------DWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDS-TENARTYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKAELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRG-VLMAAGGIEGNAEMREQAGTPGKAIWSMGPFGA-NTGDAISAGIAVG---GATALLDQAWFCPGVEQPDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPSFMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADALRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFYPGPGVPLGTAMVFSYRAAQDMAK----

General information: TITO was launched using: RESULT: Template: 4C3X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2080 20650 9.93 52.54 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 9.93 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.236

(partial model without unconserved sides chains): PDB file : Tito_4C3X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4C3X-query.scw PDB file : Tito_Scwrl_4C3X.pdb: