Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVILSDLLNRMNKSNRIQTAELDWESIDGIEVPISKQFGDVYFSKDNGLLETRHVFLNGNDLSERLANLQDFEYFSVGETGFGTGLNILALWQLWQQVR----PNNHSHLHAISVEKFPLSKADLIRALNVWDELKPLSKQLIEQYPLPLAGCHRLSFPEERFSIDLWLGDAQDIFPSMV--KTKAVNAWFLDGFAPSCN-PDMWEQNVLNNIVRLSDYGTTFASFSVAGVLKRGLKTHGIDISRPRGFGHKREMLKAVWKAPVSEEILLEPVSDTFHFTQQRIAVIGAGIAGLSTAWAFAQRGHQVTLFERT-APLSGASGNPLALLNPKPCPIEQSHEHLMTLSWQHALNFYKNFQ---AFRPIQIQQMALKNA--QDLLDLAD-QYPADIVTQ-QTS------SLESDYPHILLTEAGAVSPHQLRDEILQHQ---GIELK-IANITTLISFENKVQLKSGNETTLGADHVVVCCARESAALFE--NYPLLKPIRGQVSWVDNSFATLPLNEAYSYGGYCIQLN--ASELILGASFYPSRDDQEVLIDDHVHNFELIHSVFPHYAKQ-LPPVEQWQGRASVRAQSPDYFPLVGKMQKE-----------------------SPISTFAGLGSKGFLFAPLCSEVLVAQILGEACPVPKSLLQKLDAQRFQKKVKPKKPYFKSQ 3PS9 Chain:A ((12-671)) --------------YSIQPANLEFN------TPVSRDFDDVYFSNDNGLEETRYVFLGGNQLEVRFPEH-PHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEKFPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDAGRVTLDLWFGDINELTSQLDDSLNQKVDAWFLDGFAPAKNPD-MWTQNLFNAMARLARPGGTLATFTSAGFVRRGLQDAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPW-FNRTGSSKREAAIIGGGIASALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNFSRKDDCWLLNFAGDQQATHSVVVLANGHQISRFSQTSTLP-VYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQNPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCSAPLCAEILAAQMSDEPIPMDASTLAALNPNRLWVRKLLKGK-----

General information: TITO was launched using: RESULT: Template: 3PS9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3324 -9726 -2.93 -16.10 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -2.93 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.407

(partial model without unconserved sides chains): PDB file : Tito_3PS9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PS9-query.scw PDB file : Tito_Scwrl_3PS9.pdb: