Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLNVLKHFKEKQMPSFQSADAQINYQTFGEPSSPALVFSNSLGTNYGMWQKQFNELK-DQFFVICYDNRGHGSSSTPD-GPYTVEQLGEDVVRLLDHLNISKAAFCGISMGGLTGQWLAIHYPNRFSHVVVANTAAKIGQEQAWLDRAKLVREQGLQPIATTAASRWFTD--PFIQ--SHPSIVNNLCNDLSAGSAMGYANCCEALA--KADVREQLKDIKIPVLVIAGPQDPVTTVADGEFMQQRIPQSKLAEID-ASHISNVEQPEVFNKILKDFLVN 5A62 Chain:A ((7-268)) ----------------PSNSVSTYYEDHGDARSYPLVLIHPIGGNILIWDYEIQLLLKSGFRVIAYELRGHHRTNMGKTGAYTMQDLIDDLRRLLEHLNIGKCTIIGHSIGGIISSMYAAQHPGKVDAIIMINGSPKKFQEKDLEKHFRT-REVAITQGMKALAEHKLVSLDEARDLFADKRHADFFREVFTKTSVEGFVAATVALYTIPGNVVQGLRASGCKVFAIVGSDDDVFM-RLIKETKEEIPEMELRVLQGSDHWVVIEKPKEMYDILMGFLAI

General information: TITO was launched using: RESULT: Template: 5A62.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1388 -16553 -11.93 -65.43 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -11.93 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.486

(partial model without unconserved sides chains): PDB file : Tito_5A62.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5A62-query.scw PDB file : Tito_Scwrl_5A62.pdb: