Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPRIKVLPHAQFCPEG--AEFEVEQNANLCQSLLNKGIK-IEHACDMSCACTTCHVIVRKGF-DSLEEMNDVEADLLDRAWGLEPDSRLSCQVKVVDE---DLEIEIPKYTINHASENH 3LXF Chain:B ((9-103)) --------------DGTRTEIQAEPGLSLMEALRDAGIDELLALCGGCCSCATCHVLVAPAFADRLPALSGDENDLLDSSDHRTPHSRLSCQITIN-DKLEGLEVEIAPE---------

General information: TITO was launched using: RESULT: Template: 3LXF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 326 -7381 -22.64 -83.87 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.74 3D Compatibility (PKB) : -22.64 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.561

(partial model without unconserved sides chains): PDB file : Tito_3LXF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LXF-query.scw PDB file : Tito_Scwrl_3LXF.pdb: