Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVQVKLLDPRLGKEWPLPSYATAGSAGLDLRACLDEAIEIEPGQTVLVKTGMAIYIHDVNFAGLILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGQTT-FRLEPGERLAQYVLVPVVQAEFEQVEEFEETLRGAGGFGHTGKQ 1SLH Chain:B ((29-153)) ----------RLDPGLPLPSRAHDGDAGVDLYSA--EDVELAPGRRALVRTGVAVAV-PFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEA-------------

General information: TITO was launched using: RESULT: Template: 1SLH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 525 -59111 -112.59 -476.70 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -112.59 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.419

(partial model without unconserved sides chains): PDB file : Tito_1SLH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1SLH-query.scw PDB file : Tito_Scwrl_1SLH.pdb: