Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLPPETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWGMGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDLGEFLDVYKMSYLIE 3WR7 Chain:B ((2-162)) -----SVKLRPLEREDLRYVHQLDNNASVMRYWFE-E--PYE-AFVELSDLYDKHIHDQSERRFVVECDGEKAGLVELVEINH--VHRRAEFQIIISPEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEGELMHEFFI-NGQYRNAIRMCIFQ-

General information: TITO was launched using: RESULT: Template: 3WR7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 677 -103673 -153.14 -643.93 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.64 3D Compatibility (PKB) : -153.14 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_3WR7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WR7-query.scw PDB file : Tito_Scwrl_3WR7.pdb: