Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFTGIIESLGKVESLQSVGGDVRLRIQTDLDMSDVHLGDSIA-TNGICLTVIEWGDNWYAADVSRESLNRTTLGNWKVGQRVNVEKAMLPTTRFGGHI-VSGHVDGVGEITLVREDARSIYFEVTAPVELAKYLAEKGSVTVDGISLTINHLRGNILSLNLIPHTAERTNIGTWQVGSQVNLEVDVLARYIERLLLGDKAAEQKTESNISMAFLAENGFLK 3DDY Chain:A ((1-182)) MFRGIVQGRGVIRSISKSEDSQRHGIAFPEGMFQLVDVDTVMLVNGCSNTVVRILGDMVYFDID-QALGTTTFDGLKEGDQVNLE--IHP--------GLTGNIKGTALVAAIEENDAGFSVLIDIPKGLAENLTVKDDIGIDGISLPITDMSDSIITLNYSRDLLASTNIASLAKDVKVNVEI-------------------------------------

General information: TITO was launched using: RESULT: Template: 3DDY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 927 -47133 -50.84 -275.63 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -50.84 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_3DDY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DDY-query.scw PDB file : Tito_Scwrl_3DDY.pdb: