Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTFTLFFGVPSGCSFGSIVALEWSGLPYQLC---RIEMPAQCNTEEYRQINPVGETPALLYDNGKVLTESMAILNHIMAKSLNAAFHYEQGTEQFNLFNQKLAFLNTTLFNAFSPHWYS---LEHSSSEGNKQALREYGAVQVKKAFTALENSLTNQTWLMGDQLSFVDGYYAGIARW-LKYHNVIDIDQFPNCKRLYEQLQNEAAVKFAHAIEQE 4HZ4 Chain:A ((3-193)) --MITLHY-LKQSCSHRIVWLLEALGLDYELKIYDRLEGTGFA-PEELKAQHPLGKAP-VLQDGDLVLAEGNAIIQHLLDR-------YDT-ENRFTPAHKTDAYSNYVYWLAISASMFSANLLALVSKKGDLGDFAQYTNAQVGLYFSHVEKSLEGKTWIVGEQLTGADFALSFPLQWGLNYVNKAD---YPNITRYLEQIETHPA----------

General information: TITO was launched using: RESULT: Template: 4HZ4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 795 -36457 -45.86 -198.13 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -45.86 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_4HZ4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HZ4-query.scw PDB file : Tito_Scwrl_4HZ4.pdb: