Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKNCGSGQSKLKALRMHIYFEVDFQEQAQHYQAVLHSRGVTVDLQPIEKLNARFLRLNPDLALCVDENGLWLSAN----GMKMQPDWKA--EIPRLKRASLKSEMIARACQLGEK--PVLVDATAGLGHDSLLMAYLGAQIQLVERHPILFTLLEDSKAQAQRDPFLS-QFMDRIQLIFADSASYLKQLDQEEKTVDVVYLDPMFPQRDQNQQAIKKQAQVKKQMQLLHLLLPEDGEMDLGGHLLELAK-KVAKRVIVKRPRHAIFLANQEPAHQWQGDACRFDAYFQ 2OYR Chain:A ((31-247)) -----------------------------------------------------------NLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD---ITPRPQVVYLDPMFPHK-------QK-----KEMRVFQSLVGPD---LDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAG

General information: TITO was launched using: RESULT: Template: 2OYR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1020 6726 6.59 33.30 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 6.59 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_2OYR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OYR-query.scw PDB file : Tito_Scwrl_2OYR.pdb: