Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEV---------AYSHDEENGPIFTLRDVE--DRETYTFDSIDLIAMEIYELLY 3IMO Chain:A ((57-122)) ----AGAILWRKDD---T-NIKVMAHGADTKNVLWVTINGERYAFSYNHSS---EKIEMRKGNIQGNTIHEFDNSTP----------

General information: TITO was launched using: RESULT: Template: 3IMO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 143 -2583 -18.06 -46.96 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : -18.06 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_3IMO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IMO-query.scw PDB file : Tito_Scwrl_3IMO.pdb: