Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTALVVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVD-LASHYHFSMLAKNAKDMAAGAVLVVSLFAALTGALIFLPRIWDLLF 5D57 Chain:A ((19-125)) --------------IIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYH--ELSGRAKDLGSAAVLIAIIDAVITWAILL---------

General information: TITO was launched using: RESULT: Template: 5D57.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 215 -39240 -182.51 -370.19 target 2D structure prediction score : 0.82 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -182.51 2D Compatibility (Sec. Struct. Predict.) : 0.82 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.363

(partial model without unconserved sides chains): PDB file : Tito_5D57.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D57-query.scw PDB file : Tito_Scwrl_5D57.pdb: