Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKILITGANTGIGFATAEQLVKQGQHVILACRNPQKAQEAQNKLRSLDQGQVDVASLDLNSLELTQKAAEEIADKYGSLDVLINNAGLFSKTK---QLTVDGFEQKFGVNYLGHFLLTQKLLPVLKQFPQAHIIHLASIAHWVGSIKPNKFRAEGFYNPLFYYGQSKLANLLFSNALAEQLADSSITNNALHPGGVASDIYRDLPKPVYAAMKVGLVPTSVPAKLITEMATGDTWQNRNGEYVSAHMPDWKSSHAKNQQLARDLYQQSMNLVEKFL 2P68 Chain:A ((11-202)) ---LVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMNLLSEESINKAFEEIYNLVDGIDILVNNAGI-TRDKLFLRMSLLDWEEVLKVNLTGTFLVTQNSLRKMIKQRWGRIVNISSVVGFTGNV--------GQVN----YSTTKAGLIGFTKSLAKELAPRNVLVNAVAPGFIETDMTAVLSEEI--------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2P68.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 927 -56505 -60.95 -298.97 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -60.95 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.505

(partial model without unconserved sides chains): PDB file : Tito_2P68.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2P68-query.scw PDB file : Tito_Scwrl_2P68.pdb: