Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPK---TVVVGCDIRLSSEALKQAAIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPMDYNGMKLVRENARPISADTGLKE-IQALAETNNFEEVGQK-GTTQSYNILPEFVDHLLTYIEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNPILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQSGEKIVHDPRLVWNTFDIVDEYKGVTVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFRD--FAYCDSGMIPWLLTIVLLSETGQSLSTLVENMIAKFP---CSGEINFKVA-DTQTTIQKIFDFYADQNP-QIDRTDGVSLNFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQYYVDELTGLIQN 2FKM Chain:X ((11-444)) ----SIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGDHNPPDYNGFKIV------VAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAK--PMKVVVDCGNGVAGVIAPQLIEALGCSVIP-----LYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGF-DDGIYSAARLLEILSQDQRD----SEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIK------------

General information: TITO was launched using: RESULT: Template: 2FKM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 2760 15717 5.69 37.24 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain X : 0.76 3D Compatibility (PKB) : 5.69 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.493

(partial model without unconserved sides chains): PDB file : Tito_2FKM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2FKM-query.scw PDB file : Tito_Scwrl_2FKM.pdb: