Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELLIQPGKLTLADLRQAYLNPIKVKLDESASSAINTSVACVEQIVNEGRTAYGINTGFGLLASTKIAPEDLEKLQRSLVLSHAAGVGEALDDAMVRLIILLKANSLARGFSGIRRKVIDALLALINAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGESKARYKGEWLPAVEALKIAGLEPISLAAKEGLALLNGTQVSTAYALRGLFEAEDLFAAATVCGGLSVEAMLGSRAPFDARIHEV-RGQRGQIDVAAAYRDLLTDS------SEISR---SHEECGK--------VQDPYSLRCQPQVMGACLTQIRQAAEVLEIEANAVSDNPLVFAEQGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISMMMDRHMSQ-LPPFLVA-NGGVNSGFMIAQVTAAALASDNKALAHPASVDSLPTSANQEDHVSMAPNAGKRLWYMADNVCGILAVEWLGACQGLDFR---EGLKSSPKLEQARKILRDQVPYYSEDRFFAPDIEQASELLASGCLNELLIPKLLPSLSEV 2OHY Chain:A ((48-524)) -------------------------------------SREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLG---DLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFF-EGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIG-PASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGL--SPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRG-----------------

General information: TITO was launched using: RESULT: Template: 2OHY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2468 -108856 -44.11 -241.37 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -44.11 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_2OHY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OHY-query.scw PDB file : Tito_Scwrl_2OHY.pdb: