Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVAMSIMISTEEIQAKVKELGEQINSHYANSDKELVLIGLLRGSVIFMADLCRTITKPHELDFMTVSSYGGGTTSSRDVKILKDLDGEIRGKDVLVVEDIIDSGNTLSKVVEMLQTREPNSIQLCTLVCKPSRREIDLEVKFLGFEVEDKFIVGYGLDYDQKYRHLPFIGEIGL 4LYY Chain:A ((29-194)) ------VMITAEEIDQKLDILAEQINAHYADSDR-LLMVGLLKGSVVFMADLCRRIKGHVEIDFMSVS--------SRDVKILKDVQSEIQGRDVLIVEDLIDSGNTLNKVRDMLLLREPKSLALCTLLDKPERREVDVPVDFIGFTIPDEFIVGYGIDYAEQYRNLPYIAKV--

General information: TITO was launched using: RESULT: Template: 4LYY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 778 -139254 -178.99 -881.35 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.88 3D Compatibility (PKB) : -178.99 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.622

(partial model without unconserved sides chains): PDB file : Tito_4LYY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LYY-query.scw PDB file : Tito_Scwrl_4LYY.pdb: