Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKQIQIFFERLREQRPSPQTELKYSSPFELLIAVMLSAQATDVSVNKATDKLYPVANTAEKIYNLGVDGLKEYIKTIGLYNAKAENVIKTCKILMEQFNGEVPSNRKDLEALPGVGRKTANVVLNTAFGQPTMAVDTHIFRVGNRTGLAIG-KNVLEVEHRLV----KVIPKEFILDAHHWLILHGRYCCIARKPKCSECVVADVCNWPDRFEFGAQKQIAVKNIEAE 1MUY Chain:A ((29-208)) ---------------------------TPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYY-ARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGC----------------------

General information: TITO was launched using: RESULT: Template: 1MUY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 739 -76535 -103.57 -437.34 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -103.57 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.458

(partial model without unconserved sides chains): PDB file : Tito_1MUY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1MUY-query.scw PDB file : Tito_Scwrl_1MUY.pdb: