Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENKKPYGTVLIKASKILDYLAEN-QDVSLQTIAKGVGMTSSTVLKILDTL---LMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETIHLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLEKHPLIPYTEYTITNALRLKKEIQTVKETHIAFD-DEEIERDIFCIGASIVKNEQIIGAFSVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK 2XRN Chain:A ((16-253)) ---------VIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVEALGPAG--GFRLGPALGQLINQ--AQTDILSLVKPYLRSLAEELDESVSLASLAGDKIYVLDRIVSERE-LRVVFPIGINVPAAATAAGKVLLAALPDETLQAALGEQ--LPVLTSNTLGRKALVKQLSEVRQSGVASDLDEHI--DGVSSFATLLDTYLGYYSLAIVMPSSRASKQS-DLIKKALLQSKLNIERAIGR

General information: TITO was launched using: RESULT: Template: 2XRN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1110 -963 -0.87 -4.13 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -0.87 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_2XRN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XRN-query.scw PDB file : Tito_Scwrl_2XRN.pdb: