Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDKPVDVVHNCWGNLFNKNSQNKHIDE-----KIDYNKQSEHEDQRRENMNIKII--SVGKLKEKYLIQGINEYVKRLNAYAKIELIEVP--DEKAPE-----------NLSEAQ--MRQVKEKEGERILAKIKEQEYVYA-LAIEGKNPTSESFAKQIDQLGIQGKSHLVFVIGGSLGLSEAVMKRSNAQISFGKM-TYPHQLMRLI-LVEQIYRAFRINAGAPYHK------------------------------------------------------------------ 4DO7 Chain:A ((3-289)) -ALRIDSHQHFWRY---RAADYPWIGAGMGVLARDYLPDALHPLMHAQALGASIAVQARAGRDETAFLLELACDEARIAAVVGWEDLRAPQLAERVAEWRGTKLRGFRHQLQDEADVRAFVDDADFARGVAWLQANDYVYDVLVFERQLPDVQAFCARHDA------HWLVLDHAGKPALAEFDTALARWRAALRELAALPHVVCKLSGLVTEADWRRGLRASDLRHIEQCLDAALDAFGPQRLMFGSDWPVCLLAASYDEVASLVERWAESRLSAAERSALWGGTAARCYALP

General information: TITO was launched using: RESULT: Template: 4DO7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 822 -3138 -3.82 -16.26 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -3.82 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.235

(partial model without unconserved sides chains): PDB file : Tito_4DO7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DO7-query.scw PDB file : Tito_Scwrl_4DO7.pdb: