Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDPYTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQGIFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHTLPWGSKD--PDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEVDPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHIRFFPVDSYQMTDLPETAENIPYDTFAF-TPFMPKLNTANPEVQKYLLDIATYWIKEFDIDGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFTDSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKELMKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSLRKQLSKIISEGSTQWLIVYDREDKLY-FTRELEGQIIYVYFNQSKEPWVVEQENEVILSQNCQLLEDGKAEIRQYGFLIMC 1JF6 Chain:A ((1-541)) MLLEAIFHEAKGSYAYPISETQLRVRLRAKKGDVVRCEVLYADRYASPEEELAHAL--AGKAGSDERFDYFEALLECSTKRVKYVFLLTGPQGEAVYFGETGFSAERSKAGV-----FQYAYIHRSEVFTTPEWAKEAVIYQIFPERFANGDPSNDPPGTEQW-AKDARPRHDSFYGGDLKGVIDRLPYLEELGVTALYFTPIFASPSHHKYDTADYLAIDPQFGDLPTFRRLVDEAHRRGIKIILDAVFNHAGDQFFAFRDVLQKGEQSRYKDWFFIEDFPVSKTSRTN---------YETYAVQVPAMPKLRTENPEVKEYLFDVARFWMEQ-GIDGWRLDVANEVDHAFWREFRRLVKSLNPDALIVGEIWHDASGWLMGDQFDSVMNYLFRESVIRFFATGEIHAERFDAELTRARMLYPEQAAQGLWNLLDSHDTERFLTSCGGNEAKFRLAVLFQMTYLGTPLIYYGDEIGMAGATDPDCRRPMIWEEKEQNRGLFEFYKELIRLRHRLASLTRGNVRSWHA--DKQANLYAFVRTVQDQHVGVVLNNRGEKQTV-------------------------------

General information: TITO was launched using: RESULT: Template: 1JF6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3010 -66497 -22.09 -123.83 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -22.09 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_1JF6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JF6-query.scw PDB file : Tito_Scwrl_1JF6.pdb: