Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKTKTVVTTFDNVSIKRIA--FNFKNAGNAIAT-NCNGQLDGETEMQTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSVGEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIEN-GADEVAALELETKVMQDEF--GKFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ 1Y88 Chain:A ((16-199)) -------NLYFQGHMVARLLEEHGFETKTNVIVQGNCV-----EQEIDVVAERDGERYMIEC-KFHNIPVYTGLKEAMYTYARFLDVEKHGFTQPWIFT------NTKFSEEAKKYAGCV-GIKLTGWSY-PEKEGIEVLLESKGLYPITILRIDKEVLDELVRAGLVFCRDVVSAGEEKLREIGLSAKKAREVIAEAKKVIGGS---

General information: TITO was launched using: RESULT: Template: 1Y88.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 851 16712 19.64 93.89 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 19.64 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.244

(partial model without unconserved sides chains): PDB file : Tito_1Y88.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y88-query.scw PDB file : Tito_Scwrl_1Y88.pdb: