Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDADE-FEEADICVVATYTYDDG--DLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSVDDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI 1XYV Chain:A ((2-127)) -AKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFEGFDLVLLGCSTWGDDCIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSYEYFCGAVDAIEEKLKNLGAEIVQDGLRID----------------------

General information: TITO was launched using: RESULT: Template: 1XYV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 671 -17918 -26.70 -145.67 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -26.70 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.554

(partial model without unconserved sides chains): PDB file : Tito_1XYV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XYV-query.scw PDB file : Tito_Scwrl_1XYV.pdb: