Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHY 1A08 Chain:A ((9-91)) WYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYY

General information: TITO was launched using: RESULT: Template: 1A08.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 307 -38224 -124.51 -460.53 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : -124.51 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.614

(partial model without unconserved sides chains): PDB file : Tito_1A08.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1A08-query.scw PDB file : Tito_Scwrl_1A08.pdb: