Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHISESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQ-VPTDMFVEACKAVVRANEEYVPLYGIGGTLYLRPLLIGVGDIIGVKPA--EEYIFTIFAMPVGNYFK--GGLVPTNFLIQDEYDRAAPNGT-GAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKIEEVGSANFFGITADNEFVTP-LSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDRFVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEGWIVKVD 1I1L Chain:B ((8-308)) ---------------------------YIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKG-PVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNL--------TSAYIRPLIFVGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSS-WNRAAPNTIPTAAKAGGNYLSSLLVGSEARRHGYQEGIALDV--NGYISEGAGENLFEVKD-GVLFTPPFTSSALPGITRDAIIKLAK-ELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDG----IQVGE-GRCGPVTKRIQQAFFGLFTGETEDKWGWLDQVN

General information: TITO was launched using: RESULT: Template: 1I1L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1580 -50379 -31.89 -171.36 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.72 3D Compatibility (PKB) : -31.89 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.415

(partial model without unconserved sides chains): PDB file : Tito_1I1L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I1L-query.scw PDB file : Tito_Scwrl_1I1L.pdb: