Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQTSLSQSPNDTTSSQDVIEIKTVTRSVGRKATITKEELFQAALNLIGPQKSIASLSLREVAREAGIAPNSFYRHFKDIDELAISLIDRAGIVLRKIIRQARLRASLQDSIIRSSVEIFLQQLDADEGNLSLFLREGFTGSASYKAAVDRQLNFFQQELQEDLIRLERLNNNHLYHPELVAKAITQLVFHMGAKVIDLPIDQRAEVAEQTMIMIRMILEGARHLDEAKIR 3HIM Chain:A ((14-203)) --------------------------------TSKAAARIRAAAIEVFA-AKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSLSPEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGID-VSRWFPSHT--YSDPRIIAARYVELALRMVGCAD-----

General information: TITO was launched using: RESULT: Template: 3HIM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 805 -105535 -131.10 -555.44 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -131.10 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_3HIM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HIM-query.scw PDB file : Tito_Scwrl_3HIM.pdb: