Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNSQDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHSVQDACLGEGEGCLSVDRE-VPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEIDHINGVMFYDHINDQNPFALKEGVLVIE 2OKL Chain:B ((2-179)) MLTMKDVIREGDPILRNVAEEVSLPASEEDTTTLKEMIEFVINSQDPEMAEKYSLRPGIGLAAPQIGVSKKMIAVHVTDADG----TLYSHALFNPKIISHSVERTYLQGGEGCLSVD-REVPGYVPRYTRITVKATSINGEEVKLRLKGLPAIVFQHEIDHLNGVMFYDHINKENPFAAPDD-----

General information: TITO was launched using: RESULT: Template: 2OKL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 900 -45087 -50.10 -254.73 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.88 3D Compatibility (PKB) : -50.10 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.556

(partial model without unconserved sides chains): PDB file : Tito_2OKL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OKL-query.scw PDB file : Tito_Scwrl_2OKL.pdb: