Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLVTAIVKPFKLDDVREALSDIGVQGITVTEVKGFGRQKGHTELYRGAEYVVDFLPKVKIEIAISDEMVDAVIESITRVASTGKIGDGKIFLTNLEQVIRIRTGETGPDAV 4OZN Chain:C ((32-143)) IKLVMAIIRPDKLADVKTALAEVGAPSLTVTNVSGRGSQ-------RGEEYTVDLHQKVKVECVVADTPAEDVADAIADAAHTGEKGDGKIFILPVENAIQVRTGKTGRDAV

General information: TITO was launched using: RESULT: Template: 4OZN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 432 -59738 -138.28 -568.93 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain C : 0.83 3D Compatibility (PKB) : -138.28 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.596

(partial model without unconserved sides chains): PDB file : Tito_4OZN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OZN-query.scw PDB file : Tito_Scwrl_4OZN.pdb: