Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMNTEKLLIANRGEIAVRIIHACRDMGISSVALYADDDIGSMHVELADEAWGLAGATASETYLNIPAIIEVAKKSKATMVHPGYGFLSERAEFAQAVIDAGLKWVGPSPSAIEKLGDKIEARKIAASVGAPLVQGTQDPLENADEALEFAKQYGLPIAIKAAFGGGGRGLKVAWKLEEVKELYESAVREAKAAFGRGECFVEQYLDKPRHVEAQVIADQHGNIVVLGTRDCSLQRRNQKLVEEAPAPFISDEIYQQILSSAKNICQAANYVGAGTVEYLLSRDGKLSFLEVNTRLQVEHPVTEETSKVDLVVEQIRVAQGHKLSIKE-TPKAQGHAIEFRINAEDPARGFILAFGVLSLFEAPFGNGVRVDTGVRTGSLVSSHFDSLMAKLIITGPTREVAIARAKRALKQFKIEGVASVLDFHRAVLNEPDFTDEFNVHTRWIENDFKQELKPTKRG---------------I---PNH-Q--QP-------MLLSY-IEINGKLHRLGLPA-------------------------------------------G-------M---------FAQ-------GPATAAQAQTAEHLLAPINGVISAWKVENGEQVTEGQVVAIMEAMKMEVQVLAHRSGVIQL-SAEKGETCHAETAIASIH 3N6R Chain:G ((2-681)) ---FNKILIANRGEIACRVIKTARKMGISTVAIYSDADKQALHVQMADEAVHIGPPPANQSYIVIDKVMAAIRATGAQAVHPGYGFLSENSKFAEALEAEGVIFVGPPKGAIEAMGDKITSKKIAQEANVSTVPGYMGLIEDADEAVKISNQIGYPVMIKASA------MRIAWNDQEAREGFQSSKN--------DRIFIEKFVTQPRHIEIQVLCDSHGNGIYLGERECSIQRRNQKVVEEAPSPFLDEATRRAMGEQAVALAKAVGYASAGTVEFIVDGQKNFYFLEMNTRLQVEHPVTELITGVDLVEQMIRVAAGEPLSITQGDVKLTGWAIENRLYAEDPYRGFLPSIGRLTRYRPPAEAAVRNDTGVYEGGEISMYYDPMIAKLCTWAPTRAAAIEAMRIALDSFEVEGIGHNLPFLSAVMDHPKFISGD-MTTAFIAEEYPEGFEGVNLPETDLRRVAAAAAAMHRVAEIRRTRVSGRMDNHERRVGTEWVVTLQGADFPVTIAADHDGSTVSFDDGSSMRVTSDWTPGDQLANLMVDGAPLVLKVGKISGGFRIRTRGADLKVHVRTPRQAELARLMPEKLPPDTSKMLLCPMPGLIVKVDVEVGQEVQEGQALCTIEAMKMENILRAEKKGVVAKINASAGNSLAVDDVIMEFE

General information: TITO was launched using: RESULT: Template: 3N6R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 3124 -158241 -50.65 -288.23 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain G : 0.77 3D Compatibility (PKB) : -50.65 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.419

(partial model without unconserved sides chains): PDB file : Tito_3N6R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3N6R-query.scw PDB file : Tito_Scwrl_3N6R.pdb: