Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPRIKVLPHAQFCPEG--AEFEVEQNANLCQSLLNKGIK-IEHACDMSCACTTCHVIVRKGF-DSLEEMNDVEADLLDRA-WGLEPDSRLSCQVKVVDED---LEIEIPKYTINHASENH 4LTU Chain:A ((2-105)) -PSITFIH-----PDGRSEIVDAAIGDSAMFAALNHGIDSIVAECGGNAVCATCHVYVDDLWLAKLPPVDANEDDLLDGTASDRLPNSRLSCQIKIA-PELDGLVLRIPER---------

General information: TITO was launched using: RESULT: Template: 4LTU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 397 -14112 -35.55 -146.99 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -35.55 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.556

(partial model without unconserved sides chains): PDB file : Tito_4LTU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LTU-query.scw PDB file : Tito_Scwrl_4LTU.pdb: