Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAQSKVLITGASSGIGSVYADRFAQRGYHLILVARDTNRLDKISKDLQEKYGLQVEFIQADLSNDQDIRKIE-DVLKNDADIEILVNNAGIALNGNFLTQDRNEIEKLLTLNITAVVRLSHAMSQSLIRKGKGAIINLGSVLGLAPEFGSTIYGASKSFIQFFSQGLHLELKDH--GVHVQAVLPSATKTEIWERSGIDLSQVP-PLMDVNDLVDAALIGFDRKETITIPVLKDENQWNNFEKSRMTLLPNFSSAEVAQRYKN 1XU9 Chain:B ((26-248)) -LQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQ-SNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSG--IVHMQAAPKEECALEIIKGGALRQE-------------------------------------

General information: TITO was launched using: RESULT: Template: 1XU9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1170 -87589 -74.86 -399.95 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -74.86 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.470

(partial model without unconserved sides chains): PDB file : Tito_1XU9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XU9-query.scw PDB file : Tito_Scwrl_1XU9.pdb: