Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence EFHGMISREAADQLLI---VAEGSYLIRESQRQPGTYTLALRFGSQTRNF--------RLYYDGKHFVGEKRFESIHDLVTD 3PQZ Chain:B ((17-94)) -FHGRISREESQRLIGQQGLVDGLFLVRESQRN-QGFVLSLCHLQKVKHYLILPSEEGRLYFSMDD--GQTRFTDLLQLV--

General information: TITO was launched using: RESULT: Template: 3PQZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 213 -7237 -33.98 -111.34 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -33.98 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.531

(partial model without unconserved sides chains): PDB file : Tito_3PQZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PQZ-query.scw PDB file : Tito_Scwrl_3PQZ.pdb: